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Structure of 616-76-2
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5-Formyl-2-hydroxybenzoic acid features a strategically positioned aldehyde group flanked by a phenolic hydroxyl and a carboxylic acid, enabling dual functionalization in synthetic sequences. This ortho-substituted scaffold supports efficient coupling reactions and serves as a key intermediate in the construction of complex aromatic systems.
5-Formyl-2-hydroxybenzoic acid serves as a versatile tri-functional building block for medicinal chemistry and materials synthesis, enabling direct access to complex heterocycles via tandem condensation, cyclization, or metal-catalyzed coupling reactions. Its ortho-hydroxyl and carboxylic acid groups provide strong chelation capability and facilitate purification via crystallization or ion-exchange chromatography. The aldehyde functionality supports efficient derivatization through reductive amination, oxime formation, or transition-metal-catalyzed cross-couplings, offering robust utility in scaffold diversification and macrocyclic ring construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: