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CS-W001157 4
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Ethyl oxamate

  • CAS No. 617-36-7

  • Cat. No. CS-0008213
  • Purity≥97%
  • MDL No.MFCD00008005

*For research and further manufacturing use only, not for direct human use.

Ethyl oxamate|CS-0008213

Structure of 617-36-7

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General Information

  • CAS No. 617-36-7
  • Cat. No. CS-0008213
  • Purity ≥97%
  • MDL No. MFCD00008005
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₃
  • Molecular Weight 117.10
  • Synonym(s) Oxamidic Acid Ethyl Ester
  • SMILES NC(C(OCC)=O)=O

Description

Ethyl oxamate is a bench-stable, moisture-tolerant derivative of oxamic acid, featuring a reactive ester group that enables straightforward incorporation into synthetic sequences. This compound serves as a key precursor in the synthesis of bioactive heterocycles and peptide mimetics, offering reliable performance under standard conditions.

Application

Ethyl oxamate serves as a stable, bench-ready synthon for oxamic acid derivatives, enabling straightforward access to bioisosteric replacements in medicinal chemistry. It functions as a versatile building block in the synthesis of heterocycles and peptide mimetics, demonstrating robust compatibility with standard coupling and cyclization protocols. Its ease of handling, predictable reactivity, and clean purification profile make it well-suited for iterative synthetic workflows in API development and target-oriented synthesis.

Synthesis

  • Route1

    References

    • Siwek, Agata; Trotsko, Nazar; Wujec, Monika; Kaminski, Rafal; Paneth, Piotr Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 6 p. 344 - 344
  • Route2

    References

    • Applied Organometallic Chemistry, , vol. 24, # 5 p. 402 - 407
  • Route3
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    • In-stock
      Ethyl oxamate|CS-0008213
      617-36-7

    References

    • Journal of the American Chemical Society, , vol. 53, p. 3902

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H372-H411
Precautionary Statements : P260-P264-P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.39
  • LogP   -0.9652
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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