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Structure of 617-37-8
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2-Ethoxy-2-oxoacetic acid features a reactive ketene-like carbonyl flanked by an ethoxy group, enabling direct incorporation into esterification and cyclization cascades. This bench-stable derivative delivers high functional group tolerance in synthetic sequences requiring α-acyloxy enol equivalents.
2-Ethoxy-2-oxoacetic acid serves as a versatile synthon in carbonylative synthesis, enabling efficient access to α-alkoxy-α-keto acids and related heterocyclic scaffolds. Its inherent electrophilicity at the carbonyl carbon facilitates nucleophilic addition reactions, while the ethoxy group provides stability and ease of purification. This compound functions as a key building block in the construction of biologically relevant motifs, particularly in medicinal chemistry workflows requiring controlled ketone introduction and orthogonal functionalization.
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GHS Pictogram :
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H319-H334
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Precautionary Statements : P261-P264-P280-P285-P501
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Lot numbers can be found on the outside label of a product: