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Structure of 617-55-0
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Dimethyl (S)-(-)-malate may be used as a starting material to synthesize (-)-tulipalin B. The selective reduction of its ester group to alcohol can be accomplished using borane-dimethyl sulfide complex (BMS) in the presence of sodium tetrahydroborate.
(S)-Dimethyl 2-hydroxysuccinate serves as a stereochemically defined building block for asymmetric synthesis, enabling the construction of chiral diacid derivatives and heterocyclic scaffolds. Its hydroxyl and ester functionalities offer orthogonal reactivity for selective transformations, including derivatization, protection, or metal-catalyzed coupling reactions. The compound exhibits good bench stability and facilitates purification via standard chromatographic methods, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H317-H318
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P272-P280-P302+P352-P362+P364-P370+P378-P501
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Lot numbers can be found on the outside label of a product: