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Structure of 618446-42-7
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Benzyl 3-(hydroxymethyl)azetidine-1-carboxylate features a strained azetidine core bearing a hydroxymethyl group and a benzyl ester, enabling direct functionalization at the nitrogen. This scaffold offers enhanced solubility and stability for use in medicinal chemistry campaigns targeting bioactive heterocycles.
Benzyl 3-(hydroxymethyl)azetidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling the synthesis of azetidine-containing scaffolds prevalent in bioactive molecules. The pendant hydroxymethyl group facilitates downstream functionalization via oxidation, protection, or coupling reactions, while the benzyl ester offers convenient deprotection under mild hydrogenolysis conditions. Its bench-stable nature and compatibility with diverse reaction environments make it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: