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Structure of 61892-95-3
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This bench-stable, moisture-tolerant (5-methylpyrazin-2-yl)methanol features a pyrazine core with a terminal hydroxymethyl group, enabling direct functionalization in synthetic routes. The methyl substituent enhances electron density at the ring, facilitating nucleophilic substitution and coupling reactions under mild conditions.
(5-Methylpyrazin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazine-based scaffolds through functional group interconversions. Its primary alcohol functionality facilitates oxidation to the carboxylic acid or derivatization to esters and amides, while the electron-deficient pyrazine ring supports electrophilic substitution and transition-metal-catalyzed coupling reactions. The molecule exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: