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Structure of 619-44-3
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Methyl 4-iodobenzoate features a para-iodinated aromatic ring paired with an ester functionality, enabling direct coupling in cross-coupling reactions. This bench-stable, moisture-tolerant reagent integrates seamlessly into synthetic sequences requiring halogen-directed functionalization or transition-metal-catalyzed transformations.
Methyl 4-iodobenzoate serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient access to biaryl and substituted aromatic scaffolds. Its iodine substituent facilitates reliable coupling under standard conditions, while the methyl ester group offers orthogonal reactivity for downstream functionalization. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H411
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: