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CS-W001157 4
Total: USD 88.00

4-Hydrazinobenzoic acid

  • CAS No. 619-67-0

  • Cat. No. CS-W018098
  • Purity≥97%
  • MDL No.MFCD00007581

*For research and further manufacturing use only, not for direct human use.

4-Hydrazinobenzoic acid|CS-W018098

Structure of 619-67-0

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General Information

  • CAS No. 619-67-0
  • Cat. No. CS-W018098
  • Purity ≥97%
  • MDL No. MFCD00007581
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight 152.15
  • Synonym(s) p-Hydrazinobenzoic acid
  • SMILES O=C(O)C1=CC=C(NN)C=C1

Description

4-Hydrazinobenzoic acid was used in the synthesis of multi-substituted dihydropyrano[2,3-c]pyrazole derivatives.

Application

4-Hydrazinobenzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of hydrazide-linked heterocycles and bioconjugates. Its hydrazine functionality readily participates in condensation reactions with aldehydes and ketones, facilitating the synthesis of hydrazone derivatives under mild conditions. The carboxylic acid group provides a handle for amide coupling or derivatization, offering orthogonal reactivity in multi-step syntheses. Bench-stable and commercially available, it supports scalable applications in API development and probe design.

Synthesis

  • Route1
    • 4-Aminobenzoic acid Conivaptan Impurity|CS-0213989
      150-13-0
    • ~%
    • In-stock
      4-Hydrazinobenzoic acid|CS-W018098
      619-67-0

    References

    • Chemische Berichte, , vol. 86, p. 1073,1075

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.35
  • LogP   0.6704
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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