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Structure of 621-52-3
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1-Ethoxy-3-nitrobenzene features a para-disubstituted benzene core with an electron-deficient nitro group flanked by a bench-stable ethoxy moiety. This combination enables selective functionalization in cross-coupling reactions and facilitates incorporation into complex aromatic scaffolds under standard conditions.
1-Ethoxy-3-nitrobenzene serves as a valuable synthetic intermediate for the construction of functionalized aromatic scaffolds. Its ortho-directed nitro and ethoxy groups enable sequential functionalization, with the nitro group facilitating subsequent reduction to an amine or coupling via cross-coupling protocols. The ethoxy substituent offers stability and facilitates purification, while the overall structure exhibits compatibility with standard reaction conditions in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: