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CS-W001157 4
Total: USD 88.00

3-(2-Bromoacetyl)pyridine

  • CAS No. 6221-12-1

  • Cat. No. CS-0156834
  • Molecule weight200.03
  • Purity≥98%
  • MDL No.MFCD08273630

*For research and further manufacturing use only, not for direct human use.

3-(2-Bromoacetyl)pyridine|CS-0156834

Structure of 6221-12-1

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General Information

  • CAS No. 6221-12-1
  • Cat. No. CS-0156834
  • Purity ≥98%
  • MDL No. MFCD08273630
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO
  • Molecular Weight 200.03
  • Synonym(s) 3-(2-Bromoacetyl)
  • SMILES C1=CC(=CN=C1)C(=O)CBr

Synthesis

  • Route1
    • 1-(Pyridin-3-yl)ethanone Imatinib Impurity|CS-0229620
      350-03-8
    • ~79%
    • 3-(2-Bromoacetyl)pyridine|CS-0156834
      6221-12-1

    References

    • BRISTOL-MYERS SQUIBB COMPANY; BHIDE, Rajeev S.; DUNCIA, John V.; HYNES, John; NAIR, Satheesh K.; PITTS, William J.; KUMAR, Sreekantha R.; GARDNER, Daniel S.; MURUGESAN, Natesan; PAIDI, Venkatram Reddy; SANTELLA, Joseph B.; SISTLA, Ramesh; WU, Hong Patent: WO2014/74675 A1, 2014 ; Location in patent: Paragraph 00221 ;
  • Route2
    • 1-(Pyridin-3-yl)ethanone Imatinib Impurity|CS-0229620
      350-03-8
    • null|null
      60-29-7
    • ~87%
    • 3-(2-Bromoacetyl)pyridine|CS-0156834
      6221-12-1

    References

    • Denny, William Alexander; Hutchings, Richard H; Johnson, Douglas S; Kaltenbronn, James Stanely; Lee, Ho Huat; Leonard, Daniele Marie; Milbank, Jared Bruce John; Repine, Joseph Thomas; Rewcastle, Gordon William; White, Andrew David Patent: US2004/44057 A1, 2004 ;
  • Route3
    • null|null
      39972-50-4
    • ~%
    • 3-(2-Bromoacetyl)pyridine|CS-0156834
      6221-12-1

    References

    • Burger et al. Journal of the American Chemical Society, 1944 , vol. 66, p. 1327

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H290-H314
Precautionary Statements : P234-P260-P264-P280-P301+P330+P331-P304+P340-P363-P390-P405-P406-P501

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.6592
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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