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CS-W001157 4
Total: USD 88.00

Terephthalaldehyde

  • CAS No. 623-27-8

  • Cat. No. CS-W020006
  • Molecule weight134.13
  • Purity≥98%
  • MDL No.MFCD00006949

*For research and further manufacturing use only, not for direct human use.

Terephthalaldehyde|CS-W020006

Structure of 623-27-8

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General Information

  • CAS No. 623-27-8
  • Cat. No. CS-W020006
  • Purity ≥98%
  • MDL No. MFCD00006949
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₂
  • Molecular Weight 134.13
  • Synonym(s) 1,4-Phthalaldehyde;p-phthalaldehyde;PDA
  • SMILES O=CC1=CC=C(C=O)C=C1

Application

Terephthalaldehyde serves as a key bifunctional building block in organic synthesis, enabling the construction of rigid aromatic scaffolds and macrocyclic architectures. Its two aldehyde groups exhibit high reactivity in imine formation, oxime coupling, and condensation reactions, facilitating efficient access to functionalized heterocycles and porous materials. The compound demonstrates excellent bench stability and ease of purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      93007-21-7
    • ~96%
    • In-stock
      Terephthalaldehyde|CS-W020006
      623-27-8

    References

    • Hosseinzadeh, Rahman; Tajbakhsh, Mahmood; Shakoori, Alireza; Niaki, Mohammad Yazdani Monatshefte fur Chemie, 2004 , vol. 135, # 10 p. 1243 - 1249
  • Route2
    • 1,4-Benzenedimethanol Plerixafor Impurity|CS-0214162
      589-29-7
    • ~97%
    • In-stock
      Terephthalaldehyde|CS-W020006
      623-27-8

    References

    • Hirano, Masao; Yakabe, Sigetaka; Chikamori, Hideki; Clark, James H.; Morimoto, Takashi Journal of Chemical Research - Part S, 1998 , # 12 p. 770 - 771
  • Route3
    • null|null
      106-42-3
    • ~88%
    • In-stock
      Terephthalaldehyde|CS-W020006
      623-27-8

    References

    • Habibzadeh, Setareh; Tajbakhsh, Mahmood Journal of Chemical Research, 2009 , # 11 p. 696 - 698

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   1.3116
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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