H-Gly-Gly-Phe-OH

Name: H-Gly-Gly-Phe-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 6234-26-0
Cat. No. CS-0134043
Molecule weight279.30
Purity98%,~11%water
MDL No.MFCD00066054

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Structure of 6234-26-0

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General Information

CAS No. 6234-26-0
Cat. No. CS-0134043
Purity 98%,~11%water
MDL No. MFCD00066054
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₇N₃O₄
Molecular Weight 279.30
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CN)=O)=O

Application

H-Gly-Gly-Phe-OH serves as a well-defined tripeptide building block for peptide synthesis, offering reliable stability and straightforward purification. The N-terminal glycine enables efficient coupling without steric hindrance, while the C-terminal phenylalanine provides a robust handle for further functionalization. Its sequence supports standard Fmoc-based solid-phase protocols and demonstrates excellent compatibility with common protecting group strategies in medicinal chemistry workflows.

Synthesis

Route1
- In-stock
  
  13171-93-2
- ~16%
- In-stock
  
  6234-26-0
References
- Ganellin, C. Robin; Bishop, Paul B.; Bambal, Ramesh B.; Chan, Suzanne M. T.; Law, James K.; Marabout, Benoit; Luthra, Pratibha Mehta; Moore, Andrew N. J.; Peschard, Olivier; Bourgeat, Pierre; Rose, Christiane; Vargas, Froylan; Schwartz, Jean-Charles Journal of Medicinal Chemistry, 2000 , vol. 43, # 4 p. 664 - 674
Route2
- In-stock
  
  58822-25-6
- ~%
- In-stock
  
  6234-26-0
- 60-18-4
References
- European Journal of Organic Chemistry, , # 23 p. 5111 - 5116
Route3
- 75720-14-8
- ~%
- In-stock
  
  492-61-5
- In-stock
  
  6234-26-0
References
- Carbohydrate Research, , vol. 82, p. 31 - 44

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

TPSA 121.52
LogP -1.1266
H_Acceptors 4
H_Donors 4
Rotatable_Bonds 7

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Peptides Dipeptides and Tripeptides

Key Words

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H-Gly-Gly-Phe-OH

CAS No. 6234-26-0

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