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Structure of 62400-75-3
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5-(Hydroxymethyl)pyrrolidin-2-one is a bench-stable, moisture-tolerant heterocyclic scaffold featuring a pendant hydroxymethyl group. This functionalized pyrrolidinone integrates readily into synthetic routes requiring polar, hydrogen-bond-capable motifs. The molecule's solubility profile supports efficient incorporation in aqueous and mixed solvent systems, enabling streamlined access to bioactive derivatives.
5-(Hydroxymethyl)pyrrolidin-2-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its pyrrolidinone core exhibits favorable solubility and metabolic stability, while the pendant hydroxymethyl group facilitates downstream functionalization via oxidation, etherification, or coupling reactions. The compound demonstrates bench stability and compatibility with common protecting group strategies, making it a practical building block for targeted synthesis of pharmaceutical intermediates and macrocyclic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: