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Structure of 62451-84-7
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Methyl 2-(3-(trifluoromethyl)phenyl)acetate features a trifluoromethyl-substituted phenyl ring linked to a methyl ester-functionalized acetic acid backbone. This electron-deficient aryl moiety enhances reactivity in cross-coupling transformations and serves as a key intermediate in pharmaceutical synthesis. The compound exhibits favorable stability under standard bench conditions and demonstrates good solubility in common organic solvents, facilitating its use in iterative synthetic sequences.
Methyl 2-(3-(trifluoromethyl)phenyl)acetate serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically active scaffolds. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the ester functionality facilitates downstream transformations such as hydrolysis, reduction, or coupling reactions. Its bench-stable nature and compatibility with common reaction conditions make it well-suited for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: