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Structure of 6248-20-0
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2,4-Dihydroxy-3-methylbenzaldehyde features a unique trifunctional aromatic scaffold with ortho-dihydroxyl and methyl substituents flanking the aldehyde group. This configuration enables direct integration into polyphenolic frameworks, serving as a key building block for bioactive molecule synthesis. The electron-rich ring system enhances reactivity in coupling reactions, while the aldehyde functionality provides a handle for conjugation under mild conditions.
2,4-Dihydroxy-3-methylbenzaldehyde serves as a versatile building block in the synthesis of bioactive heterocycles and natural product analogs. Its ortho-dihydroxy motif enables reliable metal chelation and oxidation to quinones, while the aldehyde group facilitates condensation reactions, reductive amination, and Ugi-type multicomponent couplings. The methyl substituent enhances metabolic stability and provides a handle for further functionalization. This compound exhibits good bench stability and is compatible with standard purification methods, making it suitable for iterative synthesis in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: