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CS-W001157 4
Total: USD 88.00

N-(Hydroxymethyl)acetamide

  • CAS No. 625-51-4

  • Cat. No. CS-0061075
  • Molecule weight89.09
  • Purity≥95%
  • MDL No.MFCD00014417

*For research and further manufacturing use only, not for direct human use.

N-(Hydroxymethyl)acetamide|CS-0061075

Structure of 625-51-4

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General Information

  • CAS No. 625-51-4
  • Cat. No. CS-0061075
  • Purity ≥95%
  • MDL No. MFCD00014417
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇NO₂
  • Molecular Weight 89.09
  • Synonym(s) Acetamidomethanol
  • SMILES CC(NCO)=O

Description

N-(Hydroxymethyl)acetamide features a hydroxymethyl group appended to the nitrogen of acetamide, delivering enhanced solubility and reactivity in aqueous environments. This polar functionalization enables efficient coupling in peptide synthesis and bioconjugation workflows. The molecule exhibits bench-stable handling under standard conditions, with predictable behavior in nucleophilic transformations.

Synthesis

  • Route1

    References

    • Justus Liebigs Annalen der Chemie, , vol. 343, p. 265
  • Route2
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      50-00-0
    • In-stock
      N-(Hydroxymethyl)acetamide|CS-0061075
      625-51-4

    References

    • Cooney, Aidan P.; Crampton, Michael R.; Golding, Peter Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 835 - 840
  • Route3

    References

    • DE164610 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -0.9277
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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