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Structure of 6258-30-6
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This sterically hindered carboxylic acid features a para-chlorophenyl group that enhances electron-withdrawing character and improves metabolic stability. It serves as a key building block in pharmaceutical synthesis, particularly for nonsteroidal anti-inflammatory drug (NSAID) analogs, where the chlorinated aromatic moiety contributes to target receptor affinity.
2-(4-Chlorophenyl)-2-methylpropanoic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of biologically active compounds through standard carboxylic acid transformations. Its sterically hindered α-carbon enhances metabolic stability, while the para-chlorophenyl group provides favorable lipophilic character and synthetic versatility. The compound exhibits excellent bench stability and facilitates efficient derivatization via amide, ester, or acyl chloride formation, making it well-suited for high-throughput screening campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: