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N-(2-Hydroxyethyl)nicotinamide Nicorandil Impurity

  • CAS No. 6265-73-2

  • Cat. No. CS-0229204
  • Purity≥98%
  • MDL No.MFCD00547113

*For research and further manufacturing use only, not for direct human use.

N-(2-Hydroxyethyl)nicotinamide Nicorandil Impurity|CS-0229204

Structure of 6265-73-2

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General Information

  • CAS No. 6265-73-2
  • Cat. No. CS-0229204
  • Purity ≥98%
  • MDL No. MFCD00547113
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) Nicorandil Impurity 2(Nicorandil EP Impurity B)
  • SMILES OCCNC(C1=CN=CC=C1)=O

Synthesis

  • Route1

    References

    • SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. Patent: WO2006/92204 A1, 2006 ; Location in patent: Page/Page column 16-17 ;
  • Route2

    References

    • University of Florida Patent: US5017566 A1, 1991 ;
  • Route3
    • Methyl nicotinate, ≥99%|CS-1269198
      93-60-7
    • null|null
      141-43-5
    • ~98%
    • N-(2-Hydroxyethyl)nicotinamide Nicorandil Impurity|CS-0229204
      6265-73-2

    References

    • Kniess; Spies; Brandau; Johannsen Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 7 p. 605 - 614

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   62.22
  • LogP   -0.1963
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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