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CS-W001157 4
Total: USD 88.00

2-Hydroxypyrazine

  • CAS No. 6270-63-9

  • Cat. No. CS-W013733
  • Purity≥98%
  • MDL No.MFCD00233966

*For research and further manufacturing use only, not for direct human use.

2-Hydroxypyrazine|CS-W013733

Structure of 6270-63-9

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General Information

  • CAS No. 6270-63-9
  • Cat. No. CS-W013733
  • Purity ≥98%
  • MDL No. MFCD00233966
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄N₂O
  • Molecular Weight 96.09
  • Synonym(s) pyrazin-2(1H)-one
  • SMILES O=C1NC=CN=C1

Description

2-Hydroxypyrazine features a pyrazine core with a hydroxyl group at the 2-position, delivering enhanced polarity and hydrogen-bonding capacity. This configuration supports integration into bioactive scaffolds and enables directed functionalization in synthetic pathways. The compound exhibits bench-stable behavior under standard conditions and serves as a key intermediate in heterocyclic chemistry.

Application

2-Hydroxypyrazine serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyrazine core through electrophilic substitution or metal-catalyzed coupling. Its hydroxyl group facilitates derivatization via esterification, etherification, or transition-metal-mediated cross-coupling reactions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthetic sequences in medicinal chemistry and agrochemical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   -0.2301
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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