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CS-W001157 4
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Propane-1,3-diyl diacetate

  • CAS No. 628-66-0

  • Cat. No. CS-0535666
  • Purity≥98%
  • MDL No.MFCD00014983
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Propane-1,3-diyl diacetate|CS-0535666

Structure of 628-66-0

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Description

Propane-1,3-diyl diacetate is a stable, moisture-tolerant acetylating agent featuring two acetate groups flanked by a propane backbone. This bifunctional reagent enables efficient O-acetylation of alcohols and phenols under mild conditions, offering predictable regioselectivity in complex molecule synthesis.

Application

Propane-1,3-diyl diacetate serves as a stable, bench-ready acetylating agent for primary alcohols and amines under mild conditions. Its diacetate functionality enables selective O- and N-acetylation with minimal epimerization risk, offering excellent functional group tolerance and straightforward purification. This reagent facilitates efficient protection of hydroxyl and amino groups in complex molecule synthesis, particularly in carbohydrate and peptide chemistry workflows.

General Information

  • CAS No. 628-66-0
  • Cat. No. CS-0535666
  • Purity ≥98%
  • MDL No. MFCD00014983
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₄
  • Molecular Weight 160.17
  • Synonym(s) 1,3-Diacetoxypropane
  • SMILES CC(OCCCOC(C)=O)=O

Computational Chemistry Data

  • TPSA   52.6
  • LogP   0.5027
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

Safety Information

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GHS Pictogram : N/A
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Signal Word : N/A
UN#: N/A
Class : N/A
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Hazard Statements : N/A
Precautionary Statements : N/A

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