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Structure of 6280-88-2
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4-Chloro-2-nitrobenzoic acid features a chlorine substituent and a nitro group positioned ortho to the carboxylic acid, creating a highly electron-deficient aromatic system. This combination enhances reactivity in coupling reactions and facilitates direct functionalization under mild conditions. The compound serves as a key building block for pharmaceutical intermediates and specialty dyes.
4-Chloro-2-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other heterocyclic scaffolds. The ortho-nitro group facilitates directed metalation and subsequent functionalization, while the carboxylic acid enables amide coupling and salt formation. Its bench-stable crystalline form simplifies handling and purification, supporting scalable transformations in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: