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CS-W001157 4
Total: USD 88.00

(2-Methoxypyrimidin-5-yl)boronic acid

  • CAS No. 628692-15-9

  • Cat. No. CS-W004698
  • Purity≥98%
  • MDL No.MFCD03094664
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2-Methoxypyrimidin-5-yl)boronic acid|CS-W004698

Structure of 628692-15-9

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Description

This boronate moiety integrates readily into Suzuki-Miyaura couplings, offering enhanced solubility and stability under standard conditions. The methoxy group imparts electron-donating character, improving reactivity in palladium-catalyzed cross-coupling processes.

Application

(2-Methoxypyrimidin-5-yl)boronic acid serves as a versatile building block in cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyrimidine core provides enhanced stability and solubility, while the methoxy group improves functional group tolerance and facilitates downstream derivatization. The boronic acid moiety enables reliable Suzuki-Miyaura coupling with aryl and heteroaryl halides, making it particularly valuable for constructing biologically relevant scaffolds in medicinal chemistry and materials science.

General Information

  • CAS No. 628692-15-9
  • Cat. No. CS-W004698
  • Purity ≥98%
  • MDL No. MFCD03094664
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇BN₂O₃
  • Molecular Weight 153.93
  • Synonym(s) None
  • SMILES OB(C1=CN=C(OC)N=C1)O

Computational Chemistry Data

  • TPSA   75.47
  • LogP   -1.835
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501

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