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Structure of 6287-83-8
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1H-Benzo[d]imidazole-6-carbonitrile features a fused bicyclic core with a nitrile group at the 6-position, conferring high electron deficiency and enhanced metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in kinase inhibitors and fluorescent probes. The nitrile moiety enables versatile coupling reactions under mild conditions, facilitating rapid library synthesis.
1H-Benzo[d]imidazole-6-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. Its nitrile functionality offers high bench stability and compatibility with diverse reaction conditions, facilitating downstream derivatization for drug discovery applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: