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CS-W001157 4
Total: USD 88.00

6-Hydroxypyrimidine-4-carboxylic acid

  • CAS No. 6299-87-2

  • Cat. No. CS-W019789
  • Purity≥96%
  • MDL No.MFCD00023267
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Hydroxypyrimidine-4-carboxylic acid|CS-W019789

Structure of 6299-87-2

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Description

6-Hydroxypyrimidine-4-carboxylic acid features a dual functional group architecture—bearing both a hydroxyl and a carboxylic acid at distinct positions on the pyrimidine core—enabling direct conjugation in synthetic routes. This arrangement supports efficient coupling reactions, particularly in medicinal chemistry scaffolds requiring polar, hydrogen-bonding motifs. The molecule exhibits enhanced solubility in aqueous and protic solvents, facilitating handling under standard bench conditions.

Application

6-Hydroxypyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at both the C4 and C6 positions. Its dual functionality facilitates efficient synthesis of substituted pyrimidines via standard coupling, amidation, and cyclization protocols. The molecule exhibits favorable bench stability and compatibility with common protecting group strategies, supporting scalable development of heterocyclic scaffolds relevant to kinase inhibitors and antiviral agents.

General Information

  • CAS No. 6299-87-2
  • Cat. No. CS-W019789
  • Purity ≥96%
  • MDL No. MFCD00023267
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄N₂O₃
  • Molecular Weight 140.10
  • Synonym(s) Pyrimidin-6-ol-4-carboxylic acid; 6-Hydroxypyrimidine-4-carboxylic acid
  • SMILES O=C(C(N=CN1)=CC1=O)O

Computational Chemistry Data

  • TPSA   83.05
  • LogP   -0.5319
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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