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Structure of 62995-79-3
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4-Methylamino-2,2,6,6-tetramethylpiperidine is a sterically hindered amine featuring a methylamino group at the 4-position and four methyl substituents on the piperidine ring. This configuration imparts exceptional steric shielding and bench-stable basicity, enabling effective use in catalytic deprotonation and as a protective auxiliary in synthetic sequences requiring minimal nucleophilicity.
4-Methylamino-2,2,6,6-tetramethylpiperidine serves as a sterically hindered amine scaffold with enhanced basicity and nucleophilicity due to the electron-donating methylamino group at C4. Its tert-butyl-like steric shielding enables high stability under acidic and oxidative conditions, facilitating use in catalytic reactions, protecting group strategies, and as a building block for bioactive heterocycles. The molecule exhibits excellent solubility and ease of purification, making it well-suited for bench-scale synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: