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Structure of 63082-45-1
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4-Fluoro-2-methylbenzaldehyde features a fluorine atom at the para position and a methyl group at the ortho position relative to the aldehyde, creating a uniquely electron-deficient aromatic ring. This combination enhances reactivity in electrophilic substitution and facilitates efficient coupling in synthetic routes requiring directed functionalization. The aldehyde group enables direct incorporation into imines, hydrazones, and other carbonyl-derived scaffolds. Its bench-stable nature supports reliable handling under standard conditions.
4-Fluoro-2-methylbenzaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted benzimidazoles, biaryls, and heterocyclic scaffolds via standard coupling and condensation reactions. Its ortho-methyl and para-fluoro substituents provide enhanced reactivity in electrophilic aromatic substitution and facilitate downstream functionalization through directed ortho-metalation. The aldehyde functionality offers reliable access to imines, oximes, and hydrazones, while the compound exhibits good bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: