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CS-W001157 4
Total: USD 88.00

2-(1-Pyrazolyl)ethanol

  • CAS No. 6314-23-4

  • Cat. No. CS-0155605
  • Molecule weight112.13
  • Purity≥97%
  • MDL No.MFCD00046076

*For research and further manufacturing use only, not for direct human use.

2-(1-Pyrazolyl)ethanol|CS-0155605

Structure of 6314-23-4

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General Information

  • CAS No. 6314-23-4
  • Cat. No. CS-0155605
  • Purity ≥97%
  • MDL No. MFCD00046076
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₂O
  • Molecular Weight 112.13
  • Synonym(s) 2-(1H-pyrazol-1-yl)ethanol
  • SMILES C1=CN(CCO)N=C1

Description

2-(1-Pyrazolyl)ethanol features a pyrazole ring linked to an ethanolic side chain, delivering a versatile scaffold for medicinal chemistry. The polar hydroxyl group enhances solubility and enables further derivatization, while the nitrogen-rich heterocycle supports hydrogen bonding and metal coordination. This compound serves as a key building block in bioactive molecule synthesis.

Application

2-(1-Pyrazolyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-containing scaffolds through straightforward functional group transformations. Its hydroxyl group facilitates derivatization via esterification, etherification, or activation for coupling reactions, while the pyrazole ring provides robust metabolic stability and hydrogen-bonding capacity. The compound exhibits good bench stability, ease of purification, and compatibility with standard synthetic protocols, making it well-suited for high-throughput library synthesis and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   -0.1246
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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