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Structure of 6339-87-3
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Thiophene-2-sulfonamide features a sulfur-containing heterocyclic core with a sulfonamide functional group, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, offering a robust platform for medicinal chemistry applications where electron-deficient aromatic systems are required.
Thiophene-2-sulfonamide serves as a versatile building block in medicinal chemistry, offering a stable, bench-compatible scaffold for the synthesis of heterocyclic compounds. Its sulfonamide group provides strong hydrogen-bonding capacity and enhanced solubility, while the thiophene ring contributes π-conjugation and metabolic stability. The molecule participates reliably in Suzuki-Miyaura and Buchwald-Hartwig couplings, enabling efficient access to biologically active architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: