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CS-W001157 4
Total: USD 88.00

4-Chloroindoline-2,3-dione

  • CAS No. 6344-05-4

  • Cat. No. CS-W002403
  • Purity≥97%
  • MDL No.MFCD00129178
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloroindoline-2,3-dione|CS-W002403

Structure of 6344-05-4

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Description

4-Chloroindoline-2,3-dione features a chlorinated indoline core with two adjacent carbonyl groups, delivering high reactivity in cycloaddition and electrophilic substitution reactions. This electron-deficient scaffold integrates readily into complex heterocyclic architectures under mild conditions.

Application

4-Chloroindoline-2,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indole scaffolds via cycloaddition and condensation reactions. Its electrophilic C4-chloro group facilitates nucleophilic substitution under mild conditions, while the diketone moiety supports enolization and cyclization pathways. The compound exhibits good bench stability and compatibility with common functional groups, making it suitable for use in medicinal chemistry campaigns targeting heterocyclic libraries and API intermediates.

General Information

  • CAS No. 6344-05-4
  • Cat. No. CS-W002403
  • Purity ≥97%
  • MDL No. MFCD00129178
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄ClNO₂
  • Molecular Weight None
  • Synonym(s) Indole-2,3-dione, 4-chloro-
  • SMILES O=C1NC2=C(C(Cl)=CC=C2)C1=O

Computational Chemistry Data

  • TPSA   46.17
  • LogP   1.4748
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301-H319
Precautionary Statements : P264-P270-P280-P305+P351+P338-P330-P405-P501

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