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Tert-butyl 4-hydroxy-4-(3-(trifluoromethyl)phenyl)piperidine-1-carboxylate

  • CAS No. 634464-86-1

  • Cat. No. CS-0524648
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 4-hydroxy-4-(3-(trifluoromethyl)phenyl)piperidine-1-carboxylate|CS-0524648

Structure of 634464-86-1

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General Information

  • CAS No. 634464-86-1
  • Cat. No. CS-0524648
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₂F₃NO₃
  • Molecular Weight 345.36
  • Synonym(s) 1-Boc-4-[3-(trifluoromethyl)phenyl]-4-hydroxypiperidine
  • SMILES CC(C)(C)OC(=O)N1CCC(O)(C2=CC=CC(C(F)(F)F)=C2)CC1

Synthesis

  • Route1
    • null|null
      402-26-6
    • null|null
      79099-07-3
    • ~65%
    • Tert-butyl 4-hydroxy-4-(3-(trifluoromethyl)phenyl)piperidine-1-carboxylate|CS-0524648
      634464-86-1

    References

    • Gruenenthal GmbH Patent: US2009/264400 A1, 2009 ; Location in patent: Page/Page column 97 ; US 20090264400 A1

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   3.9239
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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