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Ethyl 4-hydroxy-7-methoxyquinoline-3-carboxylate

  • CAS No. 63463-15-0

  • Cat. No. CS-0134775
  • Purity≥95%
  • MDL No.MFCD00085986

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-hydroxy-7-methoxyquinoline-3-carboxylate|CS-0134775

Structure of 63463-15-0

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General Information

  • CAS No. 63463-15-0
  • Cat. No. CS-0134775
  • Purity ≥95%
  • MDL No. MFCD00085986
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃NO₄
  • Molecular Weight 247.25
  • Synonym(s) Ethyl 4-Hydroxy-7-Methoxy-3-quinolinecarboxylate
  • SMILES O=C(OCC)C1=C(C2=CC=C(C=C2N=C1)OC)O

Synthesis

  • Route1
    • null|null
      536-90-3
    • In-stock
      Diethyl 2-(ethoxymethylene)malonate|CS-0019402
      87-13-8
    • ~57%
    • In-stock
      Ethyl 4-hydroxy-7-methoxyquinoline-3-carboxylate|CS-0134775
      63463-15-0

    References

    • PFIZER INC. Patent: WO2005/21554 A1, 2005 ; Location in patent: Page/Page column 94-95 ;
  • Route2
    • null|null
      56881-19-7
    • ~86%
    • In-stock
      Ethyl 4-hydroxy-7-methoxyquinoline-3-carboxylate|CS-0134775
      63463-15-0

    References

    • Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 12 p. 2980 - 2985

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   68.65
  • LogP   2.1257
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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