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Structure of 635-27-8
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5-Chloroquinoline is a heterocyclic compound featuring a chlorine atom at the 5-position of the quinoline core. This electron-deficient scaffold serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules through cross-coupling reactions. The chloro group enhances reactivity in palladium-catalyzed transformations and contributes to favorable pharmacokinetic properties in drug candidates.
5-Chloroquinoline serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling direct functionalization at the C5 position via palladium-catalyzed cross-coupling reactions. Its electron-deficient aromatic core enhances reactivity in nucleophilic substitution processes, while maintaining bench stability and compatibility with common protecting groups. The molecule functions effectively in the synthesis of quinoline-based pharmaceuticals, agrochemicals, and ligands for transition metal catalysis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: