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CS-W001157 4
Total: USD 88.00

2-Hydroxyterephthalic acid

  • CAS No. 636-94-2

  • Cat. No. CS-W009063
  • Molecule weight182.13
  • Purity≥97%
  • MDL No.MFCD09835368

*For research and further manufacturing use only, not for direct human use.

2-Hydroxyterephthalic acid|CS-W009063

Structure of 636-94-2

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General Information

  • CAS No. 636-94-2
  • Cat. No. CS-W009063
  • Purity ≥97%
  • MDL No. MFCD09835368
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₅
  • Molecular Weight 182.13
  • Synonym(s) 2-hydroxybenzene-1,4-dioic acid
  • SMILES O=C(O)C1=CC=C(C(=O)O)C(O)=C1

Application

2-Hydroxyterephthalic acid serves as a versatile building block in the synthesis of functionalized aromatic systems and heterocyclic scaffolds. Its dual carboxylic acid and phenolic hydroxyl groups enable orthogonal derivatization, facilitating efficient conjugation in polymer chemistry and coordination complexes. The compound exhibits good bench stability and simplifies purification through crystallization, supporting scalable applications in materials science and medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • US7351856 B1, ; Page/Page column 10-11 ;
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 53, # 2 p. 439 - 440
  • Route3

    References

    • Angewandte Chemie, International Edition, , vol. 48, # 25 p. 4639 - 4642 Angewandte Chemie, , vol. 121, # 25 p. 4710 - 4714

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   94.83
  • LogP   0.7886
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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