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Structure of 637-60-5
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p-Tolylhydrazine hydrochloride offers a bench-stable, moisture-tolerant platform for constructing hydrazone-based scaffolds in synthetic and medicinal chemistry. The para-methyl group enhances electron density at the hydrazine nitrogen, improving reactivity in condensation reactions with aldehydes and ketones. This derivative facilitates efficient access to bioactive heterocycles and functionalized intermediates under standard conditions.
p-Tolylhydrazine hydrochloride serves as a reliable building block for the synthesis of heterocyclic compounds, particularly in the construction of pyrazoles and triazoles via condensation reactions. Its stability under ambient conditions and ease of handling make it well-suited for bench-scale applications. The molecule exhibits good functional group tolerance and facilitates efficient coupling with carbonyl-containing substrates, enabling straightforward access to biologically relevant scaffolds.
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GHS Pictogram :
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GHS No : GHS06,GHS08,GHS09
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331-H317-H350-H410
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Precautionary Statements : P261-P264-P270-P271-P272-P273-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P391-P405-P501
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Lot numbers can be found on the outside label of a product: