Lot numbers can be found on the outside label of a product:
Methyl 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate
-
CAS No. 6375-89-9
- Cat. No. CS-W010801
- Purity≥98%
- MDL No.MFCD00031001
*For research and further manufacturing use only, not for direct human use.
Structure of 6375-89-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 6375-89-9
- Cat. No. CS-W010801
- Purity ≥98%
- MDL No. MFCD00031001
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₉NO₃
- Molecular Weight 167.16
- Synonym(s) 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester
- SMILES O=C(C(C=C1)=CN(C)C1=O)OC
Description
Methyl 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate features a conjugated dihydropyridine core with dual carbonyl and ester functionalities, enabling direct participation in cycloaddition and condensation reactions. This bench-stable heterocycle serves as a key intermediate for nitrogen-containing scaffolds in medicinal chemistry and synthetic methodology.
Application
Methyl 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate serves as a versatile dihydropyridine scaffold for heterocyclic synthesis, enabling efficient access to substituted pyridines and pharmacologically relevant frameworks. Its enolizable carbonyl and electron-deficient double bond facilitate nucleophilic addition, cycloaddition, and transition-metal-catalyzed coupling reactions. The molecule exhibits bench stability and ease of purification, making it suitable for iterative synthetic sequences in medicinal chemistry and process development workflows.
Synthesis
-
Route1
-
74-88-4 - ~%
-
In-stock
3719-45-7 -
In-stock
6375-89-9
References
-
AstraZeneca AB; NPS PHARMACEUTICALS, INC. Patent: US2007/259862 A1, 2007 ; Location in patent: Page/Page column 29 ; US 20070259862 A1
-
-
Route2
-
67-56-1
- ~%
-
In-stock
6375-89-9
References
-
AstraZeneca AB; NPS PHARMACEUTICALS, INC. Patent: US2007/259862 A1, 2007 ; Location in patent: Page/Page column 29 ; US 20070259862 A1
-
-
Route3
-
5006-66-6 -
77-78-1
- ~%
-
In-stock
6375-89-9
References
-
Yu; Ruey J.; Van Scott; Eugene J. Patent: US4258052 A1, 1981 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 48.3
- LogP 0.1719
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6375-89-9 sigma6375-89-9 manufacturer6375-89-9 price6375-89-9 structure6375-89-9 SDSbuy 6375-89-96375-89-9 supplier6375-89-9 uses6375-89-9 molecular weightprice of 6375-89-96375-89-9 chemical name formula of 6375-89-9