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CS-W001157 4
Total: USD 88.00

Carvacrol methyl ether

  • CAS No. 6379-73-3

  • Cat. No. CS-0102932
  • Purity≥98%
  • MDL No.MFCD00216689

*For research and further manufacturing use only, not for direct human use.

Carvacrol methyl ether|CS-0102932

Structure of 6379-73-3

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General Information

  • CAS No. 6379-73-3
  • Cat. No. CS-0102932
  • Purity ≥98%
  • MDL No. MFCD00216689
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆O
  • Molecular Weight 164.25
  • Synonym(s) None
  • SMILES CC(C1=CC=C(C)C(OC)=C1)C

Description

Carvacrol methyl ether features a phenolic hydroxyl group methylation, enhancing lipophilicity and metabolic stability. This modification improves membrane permeability while retaining the bioactive cresol scaffold, making it valuable for antimicrobial and antioxidant applications in natural product derivatization workflows.

Application

Carvacrol methyl ether serves as a stable, bench-ready phenolic building block for the synthesis of bioactive aromatics and heterocyclic scaffolds. Its methylated hydroxyl group enhances solubility and stability while preserving reactivity in electrophilic substitution and coupling processes. Widely used in natural product derivatization and medicinal chemistry libraries, it functions effectively in standard etherification, Suzuki-Miyaura, and Sonogashira transformations.

Synthesis

  • Route1
    • In-stock
      Carvacrol|CS-0009729
      499-75-2
    • null|null
      74-88-4
    • ~99%
    • In-stock
      Carvacrol methyl ether|CS-0102932
      6379-73-3

    References

    • Paptchikhine, Alexander; Itto, Kaori; Andersson, Pher G. Chemical Communications, 2011 , vol. 47, # 13 p. 3989 - 3991
  • Route2
    • null|null
      127621-74-3
    • ~67%
    • In-stock
      Carvacrol methyl ether|CS-0102932
      6379-73-3

    References

    • Dulayymi, Juma'a R. Al.; Baird, Mark S. Tetrahedron, 1989 , vol. 45, # 23 p. 7601 - 7614
  • Route3

    References

    • More; Narkhede; Dalal; Mahulikar Synthetic Communications, 2007 , vol. 37, # 12 p. 1957 - 1964

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302-H315-H317-H319
Precautionary Statements : P210-P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.12702
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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