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Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

  • CAS No. 6413-10-1

  • Cat. No. CS-W005344
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate|CS-W005344

Structure of 6413-10-1

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General Information

  • CAS No. 6413-10-1
  • Cat. No. CS-W005344
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄O₄
  • Molecular Weight 174.19
  • Synonym(s) Ethyl-2-Methyl-1,3-Dioxolane -2-Acetate; Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate
  • SMILES O=C(OCC)CC1(C)OCCO1

Description

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate is a bench-stable, moisture-tolerant synthon featuring a masked α-hydroxy carbonyl equivalent. The cyclic acetal stabilizes the adjacent electrophilic center, enabling controlled C–C bond formation under mild conditions. This reagent integrates readily into complex molecule assembly, particularly in carbohydrate and natural product synthesis.

Synthesis

  • Route1

    References

    • Li, Tong-Shuang; Li, Sheng-Hui; Li, Ji-Tai; Li, Hui-Zhang Journal of Chemical Research - Part S, 1997 , # 1 p. 26 - 27
  • Route2

    References

    • Journal of Catalysis, , vol. 196, # 2 p. 345 - 351
  • Route3

    References

    • Chemische Berichte, , vol. 71, p. 1803,1807

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.76
  • LogP   0.7026
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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