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CS-W001157 4
Total: USD 88.00

2-(3-Benzamidophenyl)acetic acid

  • CAS No. 64198-92-1

  • Cat. No. CS-0161644
  • Purity≥98%
  • MDL No.MFCD10026675

*For research and further manufacturing use only, not for direct human use.

2-(3-Benzamidophenyl)acetic acid|CS-0161644

Structure of 64198-92-1

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General Information

  • CAS No. 64198-92-1
  • Cat. No. CS-0161644
  • Purity ≥98%
  • MDL No. MFCD10026675
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃NO₃
  • Molecular Weight 255.27
  • Synonym(s) None
  • SMILES O=C(O)CC1=CC=CC(NC(C2=CC=CC=C2)=O)=C1

Description

This acetic acid derivative features a benzamide-substituted phenyl moiety, delivering enhanced solubility and stability in polar solvents. The para-linked amide group enables strong hydrogen bonding, facilitating integration into bioactive scaffolds. Ideal for medicinal chemistry campaigns requiring modular, bench-stable intermediates.

Application

2-(3-Benzamidophenyl)acetic acid serves as a versatile building block for medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-amide-substituted arylacetic acid framework offers predictable reactivity in coupling and cyclization reactions, with good bench stability and straightforward purification. Functions as a key scaffold in CNS-targeted compound libraries and serves as a precursor in the development of anti-inflammatory and kinase-inhibitor candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   2.566
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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