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CS-W001157 4
Total: USD 88.00

1,2,3-Trimethoxy-5-methylbenzene

  • CAS No. 6443-69-2

  • Cat. No. CS-W017113
  • Purity≥98%
  • MDL No.MFCD00008397
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,2,3-Trimethoxy-5-methylbenzene|CS-W017113

Structure of 6443-69-2

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Description

3,4,5-Trimethoxytoluene was used as a substructure model compound in the reaction of trimethoprim with free available chlorine (i.e. HOCl).

Application

1,2,3-Trimethoxy-5-methylbenzene serves as a versatile aromatic building block in medicinal chemistry and agrochemical synthesis. Its three methoxy groups provide strong electron-donating effects, enhancing reactivity in electrophilic substitution reactions. The methyl group offers a site for further functionalization, while the trimethoxy pattern ensures good bench stability and solubility. This compound facilitates efficient access to complex heterocyclic scaffolds and is compatible with standard coupling protocols, making it a practical choice for iterative synthesis workflows.

General Information

  • CAS No. 6443-69-2
  • Cat. No. CS-W017113
  • Purity ≥98%
  • MDL No. MFCD00008397
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄O₃
  • Molecular Weight 182.22
  • Synonym(s) 3,4,5-Trimethoxytoluene; 1,2,3-Trimethoxy-5-methylbenzene
  • SMILES C1=C(C(=C(C=C1C)OC)OC)OC

Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.02082
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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