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(S)-4-Methylisoxazolidin-4-ol hydrochloride

  • CAS No. 644970-79-6

  • Cat. No. CS-0379936
  • Purity≥95%
  • MDL No.MFCD31540079

*For research and further manufacturing use only, not for direct human use.

(S)-4-Methylisoxazolidin-4-ol hydrochloride|CS-0379936

Structure of 644970-79-6

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General Information

  • CAS No. 644970-79-6
  • Cat. No. CS-0379936
  • Purity ≥95%
  • MDL No. MFCD31540079
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO₂
  • Molecular Weight 139.58
  • Synonym(s) None
  • SMILES C[C@@]1(CNOC1)O.Cl

Description

(S)-4-Methylisoxazolidin-4-ol hydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a rigid isoxazolidine core. This configurationally stable scaffold integrates readily into complex molecular architectures, offering predictable stereocontrol in asymmetric synthesis. Its polar hydroxyl and protonated amine groups enhance solubility in aqueous and protic solvents, facilitating efficient downstream functionalization.

Application

(S)-4-Methylisoxazolidin-4-ol hydrochloride serves as a chiral building block for the synthesis of bioactive heterocycles and peptidomimetics. Its stable, bench-ready form facilitates straightforward incorporation into multistep syntheses, enabling efficient access to isoxazolidine-containing scaffolds via nucleophilic displacement or cycloaddition reactions. The compound exhibits excellent functional group tolerance and predictable stereochemical control in downstream transformations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   41.49
  • LogP   -0.306
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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