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Structure of 654073-32-2
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Azetidine-1-sulfonamide features a strained four-membered azetidine ring fused to a sulfonamide group, delivering enhanced metabolic stability and improved solubility in aqueous environments. This combination enables efficient incorporation into bioactive molecules, particularly in kinase inhibitor design and central nervous system-targeted therapeutics.
Azetidine-1-sulfonamide serves as a valuable synthetic building block in medicinal chemistry, offering a strained four-membered ring system with enhanced metabolic stability. Its sulfonamide group provides strong hydrogen-bonding capacity and improves solubility, while the azetidine core enables efficient incorporation into bioactive scaffolds. The compound exhibits bench stability and compatibility with standard coupling reactions, facilitating straightforward functionalization and purification—making it well-suited for lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: