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Structure of 65487-32-3
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This fluorinated phenylpropanoic acid features a para-fluorinated aromatic ring integrated with a chiral aliphatic carboxylic acid moiety. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates lipophilicity, enabling efficient incorporation into bioactive scaffolds. Bench-stable and compatible with standard coupling protocols, this compound serves as a key building block in medicinal chemistry for targeted drug discovery.
2-(3-Fluorophenyl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard functional group transformations. Its fluorinated aryl moiety enhances metabolic stability and modulates electronic properties, while the α-methyl carboxylic acid functionality supports efficient derivatization in coupling reactions and heterocycle formation. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, facilitating integration into scalable synthetic routes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: