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CS-W001157 4
Total: USD 88.00

Racemetirosine

  • CAS No. 658-48-0

  • Cat. No. CS-D0593
  • Purity≥95%
  • MDL No.MFCD00004187
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Racemetirosine|CS-D0593

Structure of 658-48-0

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Description

α-Methyl-p-tyrosine is a synthetic analog of tyrosine featuring a methyl group at the α-position, which confers metabolic stability and enhances its utility in probing catecholamine biosynthesis. This compound serves as a potent inhibitor of aromatic L-amino acid decarboxylase, enabling precise modulation of neurotransmitter production in biochemical and neuropharmacological studies.

Application

α-Methyl-p-tyrosine serves as a well-established tyrosine analog in synthetic peptide chemistry, enabling site-specific incorporation into bioactive sequences. Its methylated α-carbon enhances metabolic stability and resistance to enzymatic degradation, making it valuable for peptidomimetic design. The phenolic hydroxyl group supports orthogonal derivatization, while the aromatic ring facilitates π-stacking interactions in target-binding domains. This compound exhibits excellent bench stability and compatibility with standard coupling protocols, facilitating efficient solid-phase and solution-phase syntheses.

General Information

  • CAS No. 658-48-0
  • Cat. No. CS-D0593
  • Purity ≥95%
  • MDL No. MFCD00004187
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₃
  • Molecular Weight 195.22
  • Synonym(s) α-Methyl-p-tyrosine
  • SMILES O=C(C(C)(CC1=CC=C(C=C1)O)N)O

Computational Chemistry Data

  • TPSA   83.55
  • LogP   0.7367
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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