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Structure of 658-48-0
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α-Methyl-p-tyrosine is a synthetic analog of tyrosine featuring a methyl group at the α-position, which confers metabolic stability and enhances its utility in probing catecholamine biosynthesis. This compound serves as a potent inhibitor of aromatic L-amino acid decarboxylase, enabling precise modulation of neurotransmitter production in biochemical and neuropharmacological studies.
α-Methyl-p-tyrosine serves as a well-established tyrosine analog in synthetic peptide chemistry, enabling site-specific incorporation into bioactive sequences. Its methylated α-carbon enhances metabolic stability and resistance to enzymatic degradation, making it valuable for peptidomimetic design. The phenolic hydroxyl group supports orthogonal derivatization, while the aromatic ring facilitates π-stacking interactions in target-binding domains. This compound exhibits excellent bench stability and compatibility with standard coupling protocols, facilitating efficient solid-phase and solution-phase syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: