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Structure of 659731-48-3
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5-Chloro-2-fluoro-4-iodopyridine is a trifunctional pyridine derivative featuring complementary halogen handles for cross-coupling reactions. The chlorine and fluorine substituents enable selective functionalization, while the iodine moiety serves as a high-reactivity partner in palladium-catalyzed transformations. This compound integrates readily into complex molecular architectures under standard conditions.
5-Chloro-2-fluoro-4-iodopyridine serves as a versatile trifunctional pyridine building block for cross-coupling and heterocyclic synthesis. The strategically positioned chloro, fluoro, and iodo substituents enable sequential or selective transformations via palladium-catalyzed coupling, nucleophilic substitution, and electrophilic functionalization. Its bench-stable nature and orthogonal reactivity profile facilitate efficient access to complex pharmaceutical scaffolds and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: