Ethyl 2-bromo-4-methylnicotinate

Name: Ethyl 2-bromo-4-methylnicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 65996-17-0
Cat. No. CS-0103544
Purity≥97%
MDL No.MFCD16610942

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-bromo-4-methylnicotinate|CS-0103544

Structure of 65996-17-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Ethyl 2-bromo-4-methylnicotinate is a brominated nicotinate ester featuring a methyl group at the 4-position and a reactive bromine at the 2-position. This configuration enables direct functionalization in cross-coupling reactions, particularly Suzuki-Miyaura and Negishi transformations. The molecule's electron-deficient pyridine ring enhances reactivity while maintaining bench-stable handling under standard conditions. It serves as a key intermediate in synthesizing bioactive heterocycles and pharmaceutical scaffolds.

Application

Ethyl 2-bromo-4-methylnicotinate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine functionality. The ester and methyl groups offer orthogonal handles for further derivatization, while the pyridine core provides stability and compatibility with standard reaction conditions. Its bench-stable nature and ease of purification make it ideal for iterative synthetic sequences in medicinal chemistry and process development.

General Information

CAS No. 65996-17-0
Cat. No. CS-0103544
Purity ≥97%
MDL No. MFCD16610942
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀BrNO₂
Molecular Weight 244.09
Synonym(s) 2-Bromo-4-methyl-nicotinic acid ethyl ester
SMILES O=C(C1=C(C)C=CN=C1Br)OCC

Computational Chemistry Data

TPSA 39.19
LogP 2.32922
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2810
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

Ethyl 2-bromo-4-methylnicotinate sigmaEthyl 2-bromo-4-methylnicotinate manufacturerEthyl 2-bromo-4-methylnicotinate priceEthyl 2-bromo-4-methylnicotinate structureEthyl 2-bromo-4-methylnicotinate SDSbuy Ethyl 2-bromo-4-methylnicotinateEthyl 2-bromo-4-methylnicotinate supplierEthyl 2-bromo-4-methylnicotinate usesEthyl 2-bromo-4-methylnicotinate molecular weightprice of Ethyl 2-bromo-4-methylnicotinateEthyl 2-bromo-4-methylnicotinate chemical name formula of Ethyl 2-bromo-4-methylnicotinate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Ethyl 2-bromo-4-methylnicotinate

CAS No. 65996-17-0

Recommended Products