2,6-Dibromo-3-hydroxypyridine

Name: 2,6-Dibromo-3-hydroxypyridine
Brand: ChemScene
Availability: InStock
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CAS No. 6602-33-1
Cat. No. CS-W023062
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2,6-Dibromo-3-hydroxypyridine|CS-W023062

Structure of 6602-33-1

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Description

2,6-Dibromo-3-hydroxypyridine features a pyridine core functionalized with bromine atoms at the 2 and 6 positions and a hydroxyl group at the 3 position. This arrangement imparts high reactivity for cross-coupling transformations while maintaining stability under standard handling conditions. The molecule serves as a key intermediate in the synthesis of brominated heterocycles used in medicinal chemistry and materials science.

Application

2,6-Dibromo-3-hydroxypyridine serves as a versatile building block for the synthesis of substituted pyridine derivatives, enabling direct functionalization at C3 via nucleophilic substitution or metal-catalyzed coupling. The hydroxyl group provides a handle for derivatization, while the dibromo substitution pattern facilitates sequential cross-coupling reactions. Its bench-stable crystalline form and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and materials science applications requiring precise heterocyclic scaffolding.

General Information

CAS No. 6602-33-1
Cat. No. CS-W023062
Purity ≥95%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃Br₂NO
Molecular Weight 252.89
Synonym(s) 2,6-Dibromo-3-pyridinol
SMILES OC1=CC=C(Br)N=C1Br

Computational Chemistry Data

TPSA 33.12
LogP 2.3122
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,6-Dibromo-3-hydroxypyridine

CAS No. 6602-33-1

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