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Structure of 66033-92-9
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3-Methylbenzo[d]isoxazol-6-ol features a fused bicyclic isoxazole scaffold with a methyl substituent at the 3-position and a phenolic hydroxyl at the 6-position. This configuration imparts enhanced solubility and stability under standard bench conditions, enabling direct incorporation into synthetic sequences without requiring protective group manipulation.
3-Methylbenzo[d]isoxazol-6-ol serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its ortho-substituted isoxazole core provides enhanced metabolic stability and facilitates regioselective functionalization. The phenolic hydroxyl group enables direct derivatization via esterification or ether formation, while the methyl substituent supports further oxidation or C–H activation. Bench-stable and compatible with standard coupling protocols, it functions effectively in late-stage modifications and scaffold diversification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: