4-Bromophenyl trifluoromethanesulfonate

Name: 4-Bromophenyl trifluoromethanesulfonate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 66107-30-0
Cat. No. CS-0322706
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromophenyl trifluoromethanesulfonate|CS-0322706

Structure of 66107-30-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 66107-30-0
Cat. No. CS-0322706
Purity ≥98%
MDL No. None
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrF₃O₃S
Molecular Weight 305.07
Synonym(s) Methanesulfonic acid, 1,1,1-trifluoro-, 4-bromophenyl ester
SMILES C1=C(C=CC(=C1)OS(=O)(=O)C(F)(F)F)Br

Description

4-Bromophenyl trifluoromethanesulfonate serves as a robust arylating agent in transition-metal-catalyzed cross-coupling reactions. The triflate group enables facile C–C bond formation under mild conditions, while the bromo substituent offers orthogonal reactivity for sequential functionalization. This bifunctional scaffold integrates seamlessly into complex molecular architectures.

Application

4-Bromophenyl trifluoromethanesulfonate serves as a reliable aryl electrophile in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. Its triflate group provides high reactivity and stability, facilitating clean transformations with broad functional group tolerance. The molecule exhibits excellent bench stability and simplifies purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials science.

Synthesis

Route1
- 106-41-2
- 358-23-6
- ~94%
- In-stock
  
  66107-30-0
References
- Jolly, Phillip I.; Fleary-Roberts, Nadia; O'Sullivan, Steven; Doni, Eswararao; Zhou, Shengze; Murphy, John A. Organic and Biomolecular Chemistry, 2012 , vol. 10, # 30 p. 5807 - 5810
Route2
- In-stock
  
  17763-67-6
- ~%
- In-stock
  
  66107-30-0
References
- Herbert, John M.; Kohler, Andrew D.; Le Strat, Franck; Whitehead, David Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 440 - 441

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.37
LogP 2.6775
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Sulfonate

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Bromophenyl trifluoromethanesulfonate sigma4-Bromophenyl trifluoromethanesulfonate manufacturer4-Bromophenyl trifluoromethanesulfonate price4-Bromophenyl trifluoromethanesulfonate structure4-Bromophenyl trifluoromethanesulfonate SDSbuy 4-Bromophenyl trifluoromethanesulfonate4-Bromophenyl trifluoromethanesulfonate supplier4-Bromophenyl trifluoromethanesulfonate uses4-Bromophenyl trifluoromethanesulfonate molecular weightprice of 4-Bromophenyl trifluoromethanesulfonate4-Bromophenyl trifluoromethanesulfonate chemical name formula of 4-Bromophenyl trifluoromethanesulfonate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromophenyl trifluoromethanesulfonate

CAS No. 66107-30-0

Recommended Products