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Structure of 66411-53-8
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(R)-(1-Methylpyrrolidin-2-yl)methanamine is a chiral amine featuring a stereodefined pyrrolidine ring with a methyl-substituted methylene tether. This configuration imparts enhanced selectivity in asymmetric synthesis, enabling efficient coupling in catalyst design and pharmaceutical intermediates. The molecule exhibits excellent solubility in common organic solvents and maintains stability under standard bench conditions.
(R)-(1-Methylpyrrolidin-2-yl)methanamine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through amine coupling and reductive amination. Its pyrrolidine core provides favorable conformational rigidity and solubility, while the N-methyl group enhances metabolic stability. The compound exhibits excellent functional group tolerance and bench stability, facilitating straightforward purification and integration into standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2920
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Class : 8,3
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Packing Group : Ⅱ
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Hazard Statements : H225-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: