2-Methyl-3-nitrobenzotrifluoride

Name: 2-Methyl-3-nitrobenzotrifluoride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 6656-49-1
Cat. No. CS-W002209
Purity≥98%
MDL No.MFCD00042322

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Methyl-3-nitrobenzotrifluoride|CS-W002209

Structure of 6656-49-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 6656-49-1
Cat. No. CS-W002209
Purity ≥98%
MDL No. MFCD00042322
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆F₃NO₂
Molecular Weight 205.13
Synonym(s) N-acetyl-2-fluorophenylalanine
SMILES FC(C1=C(C)C([N+]([O-])=O)=CC=C1)(F)F

Description

2-Methyl-3-nitrobenzotrifluoride features a trifluoromethyl group paired with a nitro substituent in close proximity, creating a highly electron-deficient aromatic core. This combination enables direct coupling reactions under mild conditions, while the methyl group provides steric guidance for regioselective functionalization. The molecule exhibits excellent stability and solubility in common organic solvents, facilitating use in cross-coupling and C–H activation processes.

Application

2-Methyl-3-nitrobenzotrifluoride serves as a versatile building block in medicinal chemistry, enabling direct introduction of trifluoromethyl and nitro functionalities adjacent to a methyl group. Its reactivity facilitates electrophilic substitution, nucleophilic aromatic substitution, and transition-metal-catalyzed coupling reactions under standard conditions. The compound exhibits bench stability and tolerates diverse functional groups, simplifying purification and integration into multi-step syntheses of bioactive molecules and pharmaceutical intermediates.

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.14
LogP 2.92202
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Methyl-3-nitrobenzotrifluoride sigma2-Methyl-3-nitrobenzotrifluoride manufacturer2-Methyl-3-nitrobenzotrifluoride price2-Methyl-3-nitrobenzotrifluoride structure2-Methyl-3-nitrobenzotrifluoride SDSbuy 2-Methyl-3-nitrobenzotrifluoride2-Methyl-3-nitrobenzotrifluoride supplier2-Methyl-3-nitrobenzotrifluoride uses2-Methyl-3-nitrobenzotrifluoride molecular weightprice of 2-Methyl-3-nitrobenzotrifluoride2-Methyl-3-nitrobenzotrifluoride chemical name formula of 2-Methyl-3-nitrobenzotrifluoride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Methyl-3-nitrobenzotrifluoride

CAS No. 6656-49-1

Recommended Products